When considering off-season use of Trenbolone Enanthate, there is something we must keep in mind. Use will help the individual control his body fat, but this does not mean body fat is impossible to gain. You must consume a level of calories above maintenance to truly grow. Thankfully, with Tren you will make better use of each calorie and the metabolic factors will also provide fat gain protection. However, there will still be a cutoff point. The use of Tren in the off-season is not a license to eat like there’s no end in site. You can still gain plenty of body fat if you don’t exercise self-control.
Because steroids are lipophilic, they diffuse easily through the cell membranes, and therefore have a very large distribution volume. In their target tissues, steroids are concentrated by an uptake mechanism which relies on their binding to intracellular proteins (or " receptors ", see below). High concentration of steroids are also found in adipose tissue, although this is not a target for hormone action. In the human male, adipose tissue contains aromatase activity, and seems to be the main source of androgen-derived estrogens found in the circulation. But most of the peripheral metabolism occurs in the liver and to some extent in the kidneys, which are the major sites of hormone inactivation and elimination, or catabolism (see below).