Injecting botox first and then to follow it immediately with a filler can risk problems with moving the botox around. There is not sufficient scientific evidence documenting the safety of both at the same time. It is not widely accepted. If the botox and restylane are used in different places then it is more okay and accepted in my opinion. I like assessing the results of the botox first and determining if the results of the botox is achieving the results that you or the client likes. If more results are desired then you can consider the filler 2 weeks later. This also allows the filler to stay longer because the muscles are not causing the dispersement of the filler and also the metabolism of the filler to be increased.
Knowledge of how to give cattle injections or shots, be it sub-subcutaneously (SQ; under the skin), intramuscularly (IM; directly into the blood supply of the muscle), or intravenously (IV; directly into the vein, usually the jugular vein), is very important in order to be able to vaccinate or treat cattle with vaccines or medicines, respectively. A cow, bull, heifer, steer or calf does not have to be sick in order to be given an injection, many cattle that are perfect healthy are required to get injections or shots for annual vaccinations or booster shots.